PDBe 3dz8

X-ray diffraction
1.9Å resolution

Crystal structure of human Rab3B GTPase bound with GDP

Released:
Source organism: Homo sapiens
Entry authors: Shen Y, Tong Y, Sukumar D, Tempel W, Loppnau P, Arrowsmith CH, Edwards AM, Bountra C, Wilkstrom M, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras-related protein Rab-3B Chain: A
Molecule details ›
Chain: A
Length: 191 amino acids
Theoretical weight: 22.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P20337 (Residues: 18-190; Coverage: 79%)
Gene name: RAB3B
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E DW
Spacegroup: C2
Unit cell:
a: 56.969Å b: 50.875Å c: 73.553Å
α: 90° β: 110.91° γ: 90°
R-values:
R R work R free
0.213 0.211 0.251
Expression system: Escherichia coli