PDBe 3dsf

X-ray diffraction
2.8Å resolution

Crystal structure of anti-osteopontin antibody 23C3 in complex with W43A mutated epitope peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Osteopontin Chain: P
Molecule details ›
Chain: P
Length: 12 amino acids
Theoretical weight: 1.24 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P10451 (Residues: 40-51; Coverage: 4%)
Gene names: BNSP, OPN, PSEC0156, SPP1
Fab fragment of anti-osteopontin antibody 23C3, Heavy chain Chain: H
Molecule details ›
Chain: H
Length: 216 amino acids
Theoretical weight: 23.13 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins
Fab fragment of anti-osteopontin antibody 23C3, Light chain Chain: L
Molecule details ›
Chain: L
Length: 213 amino acids
Theoretical weight: 23.07 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 41.73Å b: 92.058Å c: 122.104Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.244 0.241 0.297
Expression system: Not provided