PDBe 3djg

X-ray diffraction
1.8Å resolution

Catalytic cycle of human glutathione reductase near 1 A resolution

Released:
Source organism: Homo sapiens
Primary publication:
Catalytic cycle of human glutathione reductase near 1 A resolution.
J. Mol. Biol. 382 371-84 (2008)
PMID: 18638483

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione reductase, mitochondrial Chain: X
Molecule details ›
Chain: X
Length: 477 amino acids
Theoretical weight: 51.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P00390 (Residues: 45-522; Coverage: 91%)
Gene names: GLUR, GRD1, GSR
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand FAD 1 x FAD

Cofactor: Ligand NDP 1 x NDP
No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: C2
Unit cell:
a: 119.532Å b: 63.362Å c: 84.619Å
α: 90° β: 121.54° γ: 90°
R-values:
R R work R free
0.145 0.141 0.186
Expression system: Escherichia coli