PDBe 3dgq

X-ray diffraction
1.6Å resolution

Crystal structure of the glutathione transferase PI enzyme in complex with the bifunctional inhibitor, etharapta

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase P Chains: A, B
Molecule details ›
Chains: A, B
Length: 210 amino acids
Theoretical weight: 23.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09211 (Residues: 1-210; Coverage: 100%)
Gene names: FAEES3, GST3, GSTP1
Sequence domains:
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: C2
Unit cell:
a: 77.93Å b: 90.33Å c: 68.96Å
α: 90° β: 98.88° γ: 90°
R-values:
R R work R free
0.196 0.195 0.227
Expression system: Escherichia coli