PDBe 3d4j

X-ray diffraction
2.4Å resolution

Crystal structure of Human mevalonate diphosphate decarboxylase

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Diphosphomevalonate decarboxylase Chains: A, B
Molecule details ›
Chains: A, B
Length: 400 amino acids
Theoretical weight: 43.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P53602 (Residues: 1-400; Coverage: 100%)
Gene names: MPD, MVD
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P21
Unit cell:
a: 86.96Å b: 53.19Å c: 97.79Å
α: 90° β: 107.25° γ: 90°
R-values:
R R work R free
0.218 0.218 0.274
Expression system: Escherichia coli