PDBe 3csh

X-ray diffraction
1.55Å resolution

Crystal Structure of Glutathione Transferase Pi in complex with the Chlorambucil-Glutathione Conjugate

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase P Chains: A, B
Molecule details ›
Chains: A, B
Length: 209 amino acids
Theoretical weight: 23.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09211 (Residues: 2-210; Coverage: 100%)
Gene names: FAEES3, GST3, GSTP1
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand LZ6 2 x LZ6

Cofactor: Ligand GSH 2 x GSH

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: C2
Unit cell:
a: 77.346Å b: 89.358Å c: 68.946Å
α: 90° β: 98.03° γ: 90°
R-values:
R R work R free
0.18 0.17 0.2
Expression system: Escherichia coli