PDBe 3aye

X-ray diffraction
2Å resolution

Crystal structure of galectin-3 CRD domian complexed with lactose


Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Galectin-3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 135 amino acids
Theoretical weight: 15.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P17931 (Residues: 117-250; Coverage: 54%)
Gene names: LGALS3, MAC2
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P1
Unit cell:
a: 32.64Å b: 51.67Å c: 60.1Å
α: 64.37° β: 86.25° γ: 80.47°
R R work R free
0.175 0.175 0.21
Expression system: Escherichia coli