› 352d

X-ray diffraction
0.95Å resolution

THE CRYSTAL STRUCTURE OF A PARALLEL-STRANDED PARALLEL-STRANDED GUANINE TETRAPLEX AT 0.95 ANGSTROM RESOLUTION

Released:
DOI: 10.2210/pdb352d/pdb
PDB entry 352d coloured by chain, front view.
PDB entry 352d coloured by chain, side view.
PDB entry 352d coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
The crystal structure of a parallel-stranded guanine tetraplex at 0.95 A resolution.
Phillips K, Dauter Z, Murchie AI, Lilley DM, Luisi B
J Mol Biol 273 171-82 (1997)
PMID: 9367755

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-116021 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*TP*GP*GP*GP*GP*T)-3') Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
Length: 6 nucleotides
Theoretical weight: 1.88 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand NA 14 x NA
Ligand CA 9 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B, SRS BEAMLINE PX9.5
Spacegroup: P1
Unit cell:
a: 28.28Å b: 34.78Å c: 56.23Å
α: 74.31° β: 77.68° γ: 89.81°
R-values:
R R work R free
0.152 not available not available
Expression system: Not provided

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Citations

29 review citations

Quadruplex DNA: sequence, topology and structure.
Burge et al. (2006)
28 more

17 mentions without citation

Refinement of the AMBER force field for nucleic acids: improving the description of alpha/gamma conformers.
Pérez et al. (2007)
16 more