2zxe

X-ray diffraction
2.4Å resolution

Crystal structure of the sodium - potassium pump in the E2.2K+.Pi state

Released:
Source organism: Squalus acanthias

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111292 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Sodium/potassium-transporting ATPase subunit alpha Chain: A
Sodium/potassium-transporting ATPase subunit beta Chain: B
Molecule details ›
Chain: B
Length: 305 amino acids
Theoretical weight: 35.18 KDa
Source organism: Squalus acanthias
UniProt:
  • Canonical: C4IX13 (Residues: 1-305; Coverage: 100%)
Gene name: atp1b1
Sequence domains: Sodium / potassium ATPase beta chain
Structure domains:
FXYD domain-containing ion transport regulator Chain: G
Molecule details ›
Chain: G
Length: 74 amino acids
Theoretical weight: 8.23 KDa
Source organism: Squalus acanthias
UniProt:
  • Canonical: Q70Q12 (Residues: 21-94; Coverage: 100%)
Gene name: fxyd10
Sequence domains: ATP1G1/PLM/MAT8 family

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, NDG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: C2
Unit cell:
a: 223.815Å b: 50.914Å c: 163.786Å
α: 90° β: 105.12° γ: 90°
R-values:
R R work R free
0.248 0.246 0.271