PDBe 2zv8

X-ray diffraction
2.7Å resolution

Lyn Tyrosine Kinase Domain-AMP-PNP complex

Released:

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase Lyn Chain: A
Molecule details ›
Chain: A
Length: 279 amino acids
Theoretical weight: 31.81 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P25911 (Residues: 239-512; Coverage: 54%)
Gene name: Lyn
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: R3
Unit cell:
a: 127.239Å b: 127.239Å c: 54.875Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.201 0.199 0.245
Expression system: Spodoptera frugiperda