PDBe 2zkc

X-ray diffraction
1.7Å resolution

Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with bisphenol Z

Source organism: Homo sapiens
Entry authors: Matsushima A, Kakuta Y, Teramoto T, Shimohigashi Y

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Estrogen-related receptor gamma Chain: A
Molecule details ›
Chain: A
Length: 244 amino acids
Theoretical weight: 27.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P62508 (Residues: 222-458; Coverage: 52%)
Gene names: ERR3, ERRG2, ESRRG, KIAA0832, NR3B3
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P41212
Unit cell:
a: 63.839Å b: 63.839Å c: 135.894Å
α: 90° β: 90° γ: 90°
R R work R free
0.199 0.197 0.234
Expression system: Escherichia coli