PDBe 2yaa

X-ray diffraction
2.3Å resolution

Crystal structure of the autoinhibited form of mouse DAPK2 in complex with ATP

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Death-associated protein kinase 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 361 amino acids
Theoretical weight: 41.8 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8VDF3 (Residues: 11-370; Coverage: 97%)
Gene name: Dapk2
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X12
Spacegroup: P212121
Unit cell:
a: 63.1Å b: 86.02Å c: 124.42Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.216 0.271
Expression system: Escherichia coli BL21(DE3)