PDBe 2y7j

X-ray diffraction
2.5Å resolution

STRUCTURE OF HUMAN PHOSPHORYLASE KINASE, GAMMA 2

Released:
Source organism: Homo sapiens
Entry authors: Muniz JRC, Shrestha A, Savitsky P, Wang J, Rellos P, Fedorov O, Burgess-Brown N, Brenner B, Berridge G, Elkins JM, Krojer T, Vollmar M, Che KH, Von Delft F, Arrowsmith CH, Edwards AM, Weigelt J, Bountra C, Knapp S

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 365 amino acids
Theoretical weight: 42.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P15735 (Residues: 6-293; Coverage: 71%)
Gene name: PHKG2
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 87.79Å b: 91.42Å c: 164.48Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.182 0.216
Expression system: Escherichia coli BL21(DE3)