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Prion-like conversion during amyloid formation at atomic resolution

Solution NMR
PDB entry 2xks coloured by chain, ensemble of 30 models, front view.
PDB entry 2xks coloured by chain, ensemble of 30 models, side view.
PDB entry 2xks coloured by chain, ensemble of 30 models, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Beta-2-microglobulin
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-158314

Macromolecules

Beta-2-microglobulin
Chain: A
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Pfam: Immunoglobulin C1-set domain
InterPro:
CATH: Immunoglobulins
Beta-2-microglobulin in PDB entry 2xks, assembly 1, front view.
Beta-2-microglobulin in PDB entry 2xks, assembly 1, side view.
Beta-2-microglobulin in PDB entry 2xks, assembly 1, top view.
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