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Crystal structure of AnCE-lisinopril-tryptophan analogue, lisW-S complex

X-ray diffraction
1.96Å resolution
PDB entry 2x95 coloured by chain, front view.
PDB entry 2x95 coloured by chain, side view.
PDB entry 2x95 coloured by chain, top view.
Source organism: Drosophila melanogaster
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Angiotensin-converting enzyme
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-171246

Macromolecules

Angiotensin-converting enzyme
Chain: A
Length: 599 amino acids
Theoretical weight: 69.24 KDa
Source organism: Drosophila melanogaster
Expression system: Komagataella phaffii GS115
UniProt:
  • Canonical: Q10714 (Residues: 17-615; Coverage: 100%)
Gene names: Ance, CG8827, Race
Pfam: Angiotensin-converting enzyme
InterPro: Peptidase M2, peptidyl-dipeptidase A
Angiotensin-converting enzyme in PDB entry 2x95, assembly 1, front view.
Angiotensin-converting enzyme in PDB entry 2x95, assembly 1, side view.
Angiotensin-converting enzyme in PDB entry 2x95, assembly 1, top view.
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