PDBe 2x6m

X-ray diffraction
1.62Å resolution

Structure of a single domain camelid antibody fragment in complex with a C-terminal peptide of alpha-synuclein

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Alpha-synuclein Chain: B
Molecule details ›
Chain: B
Length: 9 amino acids
Theoretical weight: 1.07 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P37840 (Residues: 132-140; Coverage: 6%)
Gene names: NACP, PARK1, SNCA
HEAVY CHAIN VARIABLE DOMAIN FROM DROMEDARY Chain: A
Molecule details ›
Chain: A
Length: 126 amino acids
Theoretical weight: 13.44 KDa
Source organism: Camelus dromedarius
Expression system: Escherichia coli
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: C2221
Unit cell:
a: 60.17Å b: 63.12Å c: 62.87Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.16 0.156 0.203
Expression systems:
  • Not provided
  • Escherichia coli