PDBe 2x2a

X-ray diffraction
1.4Å resolution

Free acetyl-CypA trigonal form

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidyl-prolyl cis-trans isomerase A Chains: A, B
Molecule details ›
Chains: A, B
Length: 165 amino acids
Theoretical weight: 18.08 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62937 (Residues: 1-165; Coverage: 100%)
Gene names: CYPA, PPIA
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3221
Unit cell:
a: 64.3Å b: 64.3Å c: 173.9Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.125 0.123 0.161