PDBe 2x25

X-ray diffraction
1.2Å resolution

Free acetyl-CypA orthorhombic form

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidyl-prolyl cis-trans isomerase A Chain: B
Molecule details ›
Chain: B
Length: 169 amino acids
Theoretical weight: 18.64 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62937 (Residues: 2-165; Coverage: 99%)
  • Best match: P62937-2 (Residues: 1-105)
Gene names: CYPA, PPIA
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 42.222Å b: 52.404Å c: 89.236Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.128 0.126 0.156