PDBe 2wvi

X-ray diffraction
1.8Å resolution

CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF BUBR1

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta Chain: A
Molecule details ›
Chain: A
Length: 164 amino acids
Theoretical weight: 19.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O60566 (Residues: 57-220; Coverage: 16%)
Gene names: BUB1B, BUBR1, MAD3L, SSK1
Sequence domains: Mad3/BUB1 homology region 1

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P3221
Unit cell:
a: 62.796Å b: 62.796Å c: 90.45Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.224 0.222 0.26
Expression system: Escherichia coli BL21(DE3)