PDBe 2wel

X-ray diffraction
1.9Å resolution

Crystal structure of SU6656-bound calcium/calmodulin-dependent protein kinase II delta in complex with calmodulin

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calmodulin-2 Chain: D
Molecule details ›
Chain: D
Length: 150 amino acids
Theoretical weight: 16.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0DP24 (Residues: 1-149; Coverage: 100%)
Gene names: CALM2, CAM2, CAMB
Calcium/calmodulin-dependent protein kinase type II subunit delta Chain: A
Molecule details ›
Chain: A
Length: 327 amino acids
Theoretical weight: 37.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13557 (Residues: 10-335; Coverage: 65%)
Gene names: CAMK2D, CAMKD
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P212121
Unit cell:
a: 68.26Å b: 68.85Å c: 121.98Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.161 0.161 0.199
Expression system: Escherichia coli BL21(DE3)