PDBe 2wei

X-ray diffraction
1.65Å resolution

Crystal structure of the kinase domain of Cryptosporidium parvum calcium dependent protein kinase in complex with 3-MB-PP1


Function and Biology Details

Reaction catalysed:
ATP + D-xylulose = ADP + D-xylulose 5-phosphate. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Calmodulin-domain protein kinase 1, putative Chain: A
Molecule details ›
Chain: A
Length: 287 amino acids
Theoretical weight: 33.45 KDa
Source organism: Cryptosporidium parvum Iowa II
Expression system: Escherichia coli BL21(DE3)
  • Canonical: A3FQ16 (Residues: 70-338; Coverage: 50%)
Gene name: cgd3_920
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P43212
Unit cell:
a: 68.9Å b: 68.9Å c: 130.46Å
α: 90° β: 90° γ: 90°
R R work R free
0.197 0.196 0.229
Expression system: Escherichia coli BL21(DE3)