PDBe 2wc8

X-ray diffraction
1.88Å resolution

S100A12 complex with zinc in the absence of calcium

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein S100-A12 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 95 amino acids
Theoretical weight: 10.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P80511 (Residues: 2-92; Coverage: 99%)
Gene name: S100A12
Sequence domains: S-100/ICaBP type calcium binding domain
Structure domains: EF-hand

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P212121
Unit cell:
a: 52.991Å b: 81.83Å c: 85.725Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.171 0.236
Expression system: Escherichia coli