PDBe 2w4j

X-ray diffraction
1.3Å resolution

X-ray structure of a DAP-Kinase 2-277

Released:
Source organism: Homo sapiens
Entry authors: De Diego I, Kuper J, Lehmann F, Wilmanns M

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Death-associated protein kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 277 amino acids
Theoretical weight: 31.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P53355 (Residues: 1-277; Coverage: 19%)
Gene names: DAPK, DAPK1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P212121
Unit cell:
a: 46.844Å b: 62.336Å c: 88.345Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.132 0.131 0.159
Expression system: Escherichia coli BL21