PDBe 2w1z

X-ray diffraction
1.97Å resolution

ROP2 from Toxoplasma gondii: A virulence factor with a protein- kinase fold and no enzymatic activity.


Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
ROP 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 368 amino acids
Theoretical weight: 42.62 KDa
Source organism: Toxoplasma gondii RH
Expression system: Escherichia coli BL21
  • Canonical: Q27007 (Residues: 195-561; Coverage: 69%)
Sequence domains: Kinase-like
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2
Unit cell:
a: 187.609Å b: 51.348Å c: 125.582Å
α: 90° β: 128.65° γ: 90°
R R work R free
0.196 0.193 0.24
Expression system: Escherichia coli BL21