PDBe 2w0z

X-ray diffraction
1.7Å resolution

Grb2 SH3C (3)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
GRB2-associated-binding protein 2 Chain: B
Molecule details ›
Chain: B
Length: 9 amino acids
Theoretical weight: 958 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9UQC2 (Residues: 350-358; Coverage: 1%)
Gene names: GAB2, KIAA0571
Growth factor receptor-bound protein 2 Chain: A
Molecule details ›
Chain: A
Length: 58 amino acids
Theoretical weight: 6.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P62993 (Residues: 158-214; Coverage: 26%)
Gene names: ASH, GRB2
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21212
Unit cell:
a: 47.15Å b: 28.705Å c: 45.114Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.193 0.206
Expression systems:
  • Not provided
  • Escherichia coli BL21(DE3)