PDBe 2vva

X-ray diffraction
1.56Å resolution

Human carbonic anhydrase in complex with CO2

Released:
Source organism: Homo sapiens
Primary publication:
Structural study of X-ray induced activation of carbonic anhydrase.
Proc. Natl. Acad. Sci. U.S.A. 106 10609-13 (2009)
PMID: 19520834

Function and Biology Details

Reaction catalysed:
H(2)CO(3) = CO(2) + H(2)O. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbonic anhydrase 2 Chain: X
Molecule details ›
Chain: X
Length: 260 amino acids
Theoretical weight: 29.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P00918 (Residues: 1-260; Coverage: 100%)
Gene name: CA2
Sequence domains: Eukaryotic-type carbonic anhydrase
Structure domains: Carbonic Anhydrase II

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 5.2R
Spacegroup: P21
Unit cell:
a: 42.589Å b: 41.577Å c: 72.636Å
α: 90° β: 104.84° γ: 90°
R-values:
R R work R free
0.156 0.153 0.2
Expression system: Escherichia coli