PDBe 2vhh

X-ray diffraction
2.8Å resolution

Crystal structure of a pyrimidine degrading enzyme from Drosophila melanogaster

Released:

Function and Biology Details

Reaction catalysed:
3-ureidopropanoate + H(2)O = beta-alanine + CO(2) + NH(3)
Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pyd3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 405 amino acids
Theoretical weight: 46.12 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9VI04 (Residues: 1-386; Coverage: 100%)
Gene names: CG3027, Dmel\CG3027, Dmel_CG3027, betaAS, betaASase, pyd3
Sequence domains: Carbon-nitrogen hydrolase
Structure domains: Carbon-nitrogen hydrolase

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P21212
Unit cell:
a: 95.04Å b: 197.88Å c: 97.96Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.217 0.215 0.255
Expression system: Escherichia coli BL21(DE3)