PDBe 2vbg

X-ray diffraction
1.8Å resolution

The complex structure of the branched-chain keto acid decarboxylase (KdcA) from Lactococcus lactis with 2R-1-hydroxyethyl-deazaThDP

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Branched-chain alpha-ketoacid decarboxylase Chains: A, B
Molecule details ›
Chains: A, B
Length: 570 amino acids
Theoretical weight: 63.41 KDa
Source organism: Lactococcus lactis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6QBS4 (Residues: 1-547; Coverage: 100%)
Gene name: kdcA
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: P212121
Unit cell:
a: 65.977Å b: 108.578Å c: 146.529Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.165 0.163 0.205
Expression system: Escherichia coli BL21(DE3)