PDBe 2vay

X-ray diffraction
1.94Å resolution

Calmodulin complexed with CaV1.1 IQ peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calmodulin-1 Chain: A
Molecule details ›
Chain: A
Length: 146 amino acids
Theoretical weight: 16.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P0DP23 (Residues: 4-149; Coverage: 98%)
Gene names: CALM, CALM1, CAM, CAM1
Voltage-dependent L-type calcium channel subunit alpha-1S Chain: B
Molecule details ›
Chain: B
Length: 21 amino acids
Theoretical weight: 2.78 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q13698 (Residues: 1522-1542; Coverage: 1%)
Gene names: CACH1, CACN1, CACNA1S, CACNL1A3

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CAMD BEAMLINE GCPCC
Spacegroup: C2
Unit cell:
a: 84.92Å b: 34.67Å c: 62.98Å
α: 90° β: 113.69° γ: 90°
R-values:
R R work R free
0.218 0.218 0.272
Expression systems:
  • Escherichia coli BL21
  • Not provided