PDBe 2v8v

X-ray diffraction
2.9Å resolution

Crystal structure of mutant R322A of beta-alanine synthase from Saccharomyces kluyveri


Function and Biology Details

Reaction catalysed:
3-ureidopropanoate + H(2)O = beta-alanine + CO(2) + NH(3)
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Beta-alanine synthase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 474 amino acids
Theoretical weight: 51.92 KDa
Source organism: Lachancea kluyveri
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q96W94 (Residues: 2-455; Coverage: 100%)
Gene name: PYD3
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P1
Unit cell:
a: 77.478Å b: 84.903Å c: 104.848Å
α: 67.45° β: 67.81° γ: 62.75°
R R work R free
0.196 0.194 0.246
Expression system: Escherichia coli BL21(DE3)