PDBe 2v8g

X-ray diffraction
2.5Å resolution

Crystal structure of beta-alanine synthase from Saccharomyces kluyveri in complex with the product beta-alanine

Released:

Function and Biology Details

Reaction catalysed:
3-ureidopropanoate + H(2)O = beta-alanine + CO(2) + NH(3)
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-alanine synthase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 474 amino acids
Theoretical weight: 52.01 KDa
Source organism: Lachancea kluyveri
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96W94 (Residues: 2-455; Coverage: 100%)
Gene name: PYD3
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21
Unit cell:
a: 50.1Å b: 217.3Å c: 81.6Å
α: 90° β: 91.9° γ: 90°
R-values:
R R work R free
0.191 0.189 0.231
Expression system: Escherichia coli BL21(DE3)