PDBe 2v7o

X-ray diffraction
2.25Å resolution

Crystal structure of human calcium-calmodulin-dependent protein kinase II gamma

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium/calmodulin-dependent protein kinase type II subunit gamma Chain: A
Molecule details ›
Chain: A
Length: 336 amino acids
Theoretical weight: 38.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13555 (Residues: 3-315; Coverage: 56%)
  • Best match: Q13555-6 (Residues: 3-317)
Gene names: CAMK, CAMK-II, CAMK2G, CAMKG
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: C2221
Unit cell:
a: 84.703Å b: 117.226Å c: 75.968Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.176 0.241
Expression system: Escherichia coli BL21(DE3)