PDBe 2v5y

X-ray diffraction
3.1Å resolution

Crystal structure of the receptor protein tyrosine phosphatase mu ectodomain

Released:

Function and Biology Details

Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Receptor-type tyrosine-protein phosphatase mu Chain: A
Molecule details ›
Chain: A
Length: 731 amino acids
Theoretical weight: 81.7 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P28827 (Residues: 21-742; Coverage: 50%)
Gene names: PTPRL1, PTPRM
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2
Unit cell:
a: 167.336Å b: 69.325Å c: 97.487Å
α: 90° β: 113.52° γ: 90°
R-values:
R R work R free
0.246 0.242 0.32
Expression system: Homo sapiens