EC 3.4.23.15: Renin
Reaction catalysed:
Cleavage of Leu-|- bond in angiotensinogen to generate angiotensin I.
Alternative Name(s):
- Angiotensin-forming enzyme
- Angiotensinogenase
GO terms
Biochemical function:
Biological process:
Cellular component:
- not assigned
Protein family (Pfam)![The deposited structure of PDB entry 2v11 contains 2 copies of Pfam domain PF00026 (Eukaryotic aspartyl protease) in Renin. Showing 1 copy in chain A [auth C].](https://www.ebi.ac.uk/pdbe/static/entry/2v11_1_C_Pfam_PF00026_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2v11</span> contains 2 copies of Pfam domain <span class='highlight'>PF00026 (Eukaryotic aspartyl protease)</span> in <span class='highlight'>Renin</span>. Showing 1 copy in chain <span class='highlight'>A [auth C]</span>.")
InterPro annotations
CATH domain![The deposited structure of PDB entry 2v11 contains 4 copies of CATH domain 2.40.70.10 (Cathepsin D, subunit A; domain 1) in Renin. Showing 2 copies in chain A [auth C].](https://www.ebi.ac.uk/pdbe/static/entry/2v11_1_C_CATH_2.40.70.10_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2v11</span> contains 4 copies of CATH domain <span class='highlight'>2.40.70.10 (Cathepsin D, subunit A; domain 1)</span> in <span class='highlight'>Renin</span>. Showing 2 copies in chain <span class='highlight'>A [auth C]</span>.")