PDBe 2v01

X-ray diffraction
2.15Å resolution

Recombinant vertebrate calmodulin complexed with Pb

Released:
Source organism: Homo sapiens
Primary publication:
A structural insight into lead neurotoxicity and calmodulin activation by heavy metals.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 63 653-6 (2007)
PMID: 17671360

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calmodulin-1 Chain: A
Molecule details ›
Chain: A
Length: 149 amino acids
Theoretical weight: 16.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP23 (Residues: 1-149; Coverage: 100%)
Gene names: CALM, CALM1, CAM, CAM1

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I911-2
Spacegroup: P1
Unit cell:
a: 24.58Å b: 29.95Å c: 53.61Å
α: 88.57° β: 87.03° γ: 82.95°
R-values:
R R work R free
0.191 0.188 0.253
Expression system: Escherichia coli