PDBe 2uzt

X-ray diffraction
2.1Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
cAMP-dependent protein kinase inhibitor alpha Chain: B
Molecule details ›
Chain: B
Length: 20 amino acids
Theoretical weight: 2.23 KDa
Source organism: Bos taurus
Expression system: Not provided
  • Canonical: Q3SX13 (Residues: 6-25; Coverage: 26%)
Gene name: PKIA
cAMP-dependent protein kinase catalytic subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 336 amino acids
Theoretical weight: 39.22 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
  • Canonical: P00517 (Residues: 16-351; Coverage: 96%)
Gene name: PRKACA
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 59.165Å b: 78.262Å c: 100.846Å
α: 90° β: 90° γ: 90°
R R work R free
0.273 0.273 0.313
Expression systems:
  • Not provided
  • Escherichia coli