Assemblies
Assembly Name:
Cyclin A2-CDK2 complex
Multimeric state:
hetero dimer
Accessible surface area:
23532.91 Å2
Buried surface area:
3958.52 Å2
Dissociation area:
1,592.94
Å2
Dissociation energy (ΔGdiss):
13.61
kcal/mol
Dissociation entropy (TΔSdiss):
13.16
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-148886
Assembly Name:
Cyclin A2-CDK2 complex
Multimeric state:
hetero dimer
Accessible surface area:
23482.63 Å2
Buried surface area:
3931.81 Å2
Dissociation area:
1,586.13
Å2
Dissociation energy (ΔGdiss):
11.11
kcal/mol
Dissociation entropy (TΔSdiss):
13.15
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-148886
Macromolecules
Chains: A, C
Length: 298 amino acids
Theoretical weight: 34.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Pfam: Protein kinase domain
InterPro:
Length: 298 amino acids
Theoretical weight: 34.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P24941 (Residues: 1-298; Coverage: 100%)
Pfam: Protein kinase domain
InterPro:
- Protein kinase-like domain superfamily
- Protein kinase domain
- Protein kinase, ATP binding site
- Serine/threonine-protein kinase, active site
Chains: B, D
Length: 258 amino acids
Theoretical weight: 29.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Pfam:
InterPro:
SCOP: Cyclin
Length: 258 amino acids
Theoretical weight: 29.62 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical: P20248 (Residues: 175-432; Coverage: 60%)
Pfam:
InterPro:
- Cyclin A/B-like
- Cyclin-like superfamily
- Cyclin
- Cyclin, N-terminal
- Cyclin-like domain
- Cyclin, C-terminal domain
SCOP: Cyclin
