PDBe 2tdt

X-ray diffraction
2Å resolution

COMPLEX OF TETRAHYDRODIPICOLINATE N-SUCCINYLTRANSFERASE WITH 2-AMINOPIMELATE AND COENZYME A

Released:

Function and Biology Details

Reaction catalysed:
Succinyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H(2)O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate. 
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase Chain: A
Molecule details ›
Chain: A
Length: 274 amino acids
Theoretical weight: 29.92 KDa
Source organism: Mycobacterium bovis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P56220 (Residues: 1-274; Coverage: 100%)
Gene name: dapD
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: R3
Unit cell:
a: 95.71Å b: 95.71Å c: 72.79Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.171 0.169 0.24
Expression system: Escherichia coli BL21(DE3)