PDBe 2rpn

Solution NMR

A crucial role for high intrinsic specificity in the function of yeast SH3 domains

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Actin-binding protein Chain: A
Molecule details ›
Chain: A
Length: 59 amino acids
Theoretical weight: 6.73 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P15891 (Residues: 535-592; Coverage: 10%)
Gene names: ABP1, YCR088W, YCR88W
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Actin-regulating kinase 1 Chain: B
Molecule details ›
Chain: B
Length: 18 amino acids
Theoretical weight: 1.99 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P53974 (Residues: 605-621; Coverage: 3%)
Gene names: ARK1, N2823, YNL020C

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli