PDBe 2rk3

X-ray diffraction
1.05Å resolution

Structure of A104T DJ-1

Released:

Function and Biology Details

Reaction catalysed:
An N(6)-(1-hydroxy-2-oxopropyl)-[protein]-L-lysine + H(2)O = a [protein]-L-lysine + (R)-lactate

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein/nucleic acid deglycase DJ-1 Chain: A
Molecule details ›
Chain: A
Length: 197 amino acids
Theoretical weight: 21.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q99497 (Residues: 1-189; Coverage: 100%)
Gene name: PARK7
Sequence domains: DJ-1/PfpI family
Structure domains: Rossmann fold

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P3121
Unit cell:
a: 74.78Å b: 74.78Å c: 74.99Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.133 0.132 0.15
Expression system: Escherichia coli BL21(DE3)