2rft

X-ray diffraction
2.8Å resolution

Crystal structure of influenza B virus hemagglutinin in complex with LSTa receptor analog

Released:
Primary publication:
Structural basis for receptor specificity of influenza B virus hemagglutinin.
Proc Natl Acad Sci U S A 104 16874-9 (2007)
PMID: 17942670

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-137050 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Hemagglutinin HA1 chain Chain: A
Molecule details ›
Chain: A
Length: 344 amino acids
Theoretical weight: 37.16 KDa
Source organism: Influenza B virus (B/Hong Kong/8/1973)
Expression system: Influenza B virus
UniProt:
  • Canonical: P03462 (Residues: 9-352; Coverage: 60%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains:
Hemagglutinin HA2 chain Chain: B
Molecule details ›
Chain: B
Length: 176 amino acids
Theoretical weight: 18.95 KDa
Source organism: Influenza B virus (B/Hong Kong/8/1973)
Expression system: Influenza B virus
UniProt:
  • Canonical: P03462 (Residues: 353-528; Coverage: 31%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin Ectodomain; Chain B

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: BGC, GAL, NDG, SIA
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: P321
Unit cell:
a: 98.328Å b: 98.328Å c: 135.988Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.282 0.28 0.299
Expression system: Influenza B virus