PDBe 2rei

X-ray diffraction
1.6Å resolution

Kinase domain of human ephrin type-A receptor 7 (Epha7)

Released:
Source organism: Homo sapiens
Entry authors: Walker JR, Cuerrier D, Butler-Cole C, Weigelt J, Arrowsmith CH, Edwards AM, Bochkarev A, Dhe-Paganon S, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ephrin type-A receptor 7 Chain: A
Molecule details ›
Chain: A
Length: 318 amino acids
Theoretical weight: 36.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15375 (Residues: 590-899; Coverage: 32%)
Gene names: EHK3, EPHA7, HEK11
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P65
Unit cell:
a: 51.88Å b: 51.88Å c: 215.5Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.164 0.163 0.187
Expression system: Escherichia coli BL21(DE3)