› 2rbl

X-ray diffraction
2.1Å resolution

High resolution design of a protein loop

Released:
DOI: 10.2210/pdb2rbl/pdb
PDB entry 2rbl coloured by chain, front view.
PDB entry 2rbl coloured by chain, side view.
PDB entry 2rbl coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
High-resolution design of a protein loop.
Hu X, Wang H, Ke H, Kuhlman B
Proc Natl Acad Sci U S A 104 17668-73 (2007)
PMID: 17971437

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150293 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tenascin Chains: A, B, M
Molecule details ›
Chains: A, B, M
Length: 104 amino acids
Theoretical weight: 11.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P24821 (Residues: 802-893; Coverage: 4%)
Gene names: HXB, TNC
Sequence domains: Fibronectin type III domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: R32
Unit cell:
a: 137.2Å b: 137.2Å c: 86.682Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.25 0.25 0.3
Expression system: Escherichia coli

Quick links

Citations

14 review citations

Computer-aided antibody design.
Kuroda et al. (2012)
13 more

4 mentions without citation

High-resolution design of a protein loop.
Hu et al. (2007)
3 more