› 2r73

X-ray diffraction
2.5Å resolution

Crystal Structure of the Possum Milk Whey Lipocalin Trichosurin at pH 8.2

Released:
DOI: 10.2210/pdb2r73/pdb
PDB entry 2r73 coloured by chain, front view.
PDB entry 2r73 coloured by chain, side view.
PDB entry 2r73 coloured by chain, top view.
Source organism: Trichosurus vulpecula
Primary publication:
Three-dimensional structure and ligand binding properties of trichosurin, a metatherian lipocalin from the milk whey of the common brushtail possum Trichosurus vulpecula.
Watson RP, Demmer J, Baker EN, Arcus VL
Biochem J 408 29-38 (2007)
PMID: 17685895

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173345 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Trichosurin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 166 amino acids
Theoretical weight: 19.71 KDa
Source organism: Trichosurus vulpecula
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q29147 (Residues: 16-180; Coverage: 100%)
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P43212
Unit cell:
a: 101.156Å b: 101.156Å c: 140.557Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.217 0.217 0.269
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Marsupial milk: a fluid source of nutrition and immune factors for the developing pouch young.
Pharo EA. (2019)
4 other articles

3 mentions without citation

The major cockroach allergen Bla g 4 binds tyramine and octopamine.
Offermann et al. (2014)
2 more