› 2r6f

X-ray diffraction
3.2Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177357 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
UvrABC system protein A Chains: A, B
Molecule details ›
Chains: A, B
Length: 972 amino acids
Theoretical weight: 108.78 KDa
Source organism: Geobacillus stearothermophilus 10
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5KVB6 (Residues: 4-955; Coverage: 100%)
Gene names: GK3085, uvrA
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand ADP 4 x ADP
Ligand ZN 6 x ZN
1 modified residue:
Ligand MSE 34 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P21
Unit cell:
a: 102.713Å b: 94.72Å c: 130.481Å
α: 90° β: 108.8° γ: 90°
R-values:
R R work R free
0.257 0.253 0.292
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

13 review citations

Structure, function, and evolution of bacterial ATP-binding cassette systems.
Davidson et al. (2008)
12 more

19 mentions without citation

XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase.
Fuss et al. (2011)
18 more