PDBe 2r5t

X-ray diffraction
1.9Å resolution

Crystal Structure of Inactive Serum and Glucocorticoid- Regulated Kinase 1 in Complex with AMP-PNP


Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Serine/threonine-protein kinase Sgk1 Chain: A
Molecule details ›
Chain: A
Length: 373 amino acids
Theoretical weight: 42.3 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
  • Canonical: O00141 (Residues: 60-431; Coverage: 86%)
Gene names: SGK, SGK1
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P6522
Unit cell:
a: 97.873Å b: 97.873Å c: 147.848Å
α: 90° β: 90° γ: 120°
R R work R free
0.193 0.191 0.215
Expression system: unidentified baculovirus