Function and Biology

Functional architecture of the retromer cargo-recognition complex

Source organism: Homo sapiens
Biochemical function: protein transporter activity
Biological process: retrograde transport, endosome to Golgi
Cellular component: retromer complex

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF12850
Domain description: Calcineurin-like phosphoesterase superfamily domain
Occurring in:
  1. Vacuolar protein sorting-associated protein 29
1 copy of Pfam domain PF12850 (Calcineurin-like phosphoesterase superfamily domain) in Vacuolar protein sorting-associated protein 29 in PDB 2r17.

InterPro InterPro annotations
IPR029052
Domain description: Metallo-dependent phosphatase-like
Occurring in:
  1. Vacuolar protein sorting-associated protein 29
IPR028661
Domain description: Vacuolar protein sorting-associated protein 29
Occurring in:
  1. Vacuolar protein sorting-associated protein 29
IPR005378
Domain description: Vacuolar protein sorting-associated protein 35
Occurring in:
  1. Vacuolar protein sorting-associated protein 35
IPR000979
Domain description: Phosphodiesterase MJ0936/Vps29
Occurring in:
  1. Vacuolar protein sorting-associated protein 29
IPR011989
Domain description: Armadillo-like helical
Occurring in:
  1. Vacuolar protein sorting-associated protein 35
IPR024654
Domain description: Calcineurin-like phosphoesterase domain, lpxH type
Occurring in:
  1. Vacuolar protein sorting-associated protein 29

Structure domain

CATH CATH domain
3.60.21.10
Class: Alpha Beta
Architecture: 4-Layer Sandwich
Topology: Purple Acid Phosphatase; chain A, domain 2
Homology: Purple Acid Phosphatase; chain A, domain 2
Occurring in:
  1. Vacuolar protein sorting-associated protein 29
1 copy of CATH domain 3.60.21.10 (Purple Acid Phosphatase; chain A, domain 2) in Vacuolar protein sorting-associated protein 29 in PDB 2r17.
SCOP SCOP annotation
111233
Class: Alpha and beta proteins (a+b)
Fold: Metallo-dependent phosphatases
Superfamily: Metallo-dependent phosphatases
Occurring in:
  1. Vacuolar protein sorting-associated protein 29
1 copy of SCOP domain 111233 (YfcE-like) in Vacuolar protein sorting-associated protein 29 in PDB 2r17.