Assemblies
Assembly Name:
Tyrosine-protein kinase ABL1
Multimeric state:
monomeric
Accessible surface area:
13328.1 Å2
Buried surface area:
842.68 Å2
Dissociation area:
421.34
Å2
Dissociation energy (ΔGdiss):
-2.11
kcal/mol
Dissociation entropy (TΔSdiss):
4.75
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-132624
Assembly Name:
Tyrosine-protein kinase ABL1
Multimeric state:
monomeric
Accessible surface area:
14402.58 Å2
Buried surface area:
814.62 Å2
Dissociation area:
407.31
Å2
Dissociation energy (ΔGdiss):
-1.93
kcal/mol
Dissociation entropy (TΔSdiss):
4.75
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-132624
Macromolecules
Chains: A, B
Length: 288 amino acids
Theoretical weight: 33.24 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
SCOP: Protein kinases, catalytic subunit
Length: 288 amino acids
Theoretical weight: 33.24 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
P00520 (Residues: 229-515; Coverage: 26%)
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
- Protein kinase-like domain superfamily
- Protein kinase domain
- Serine-threonine/tyrosine-protein kinase, catalytic domain
- Tyrosine-protein kinase, catalytic domain
- Protein kinase, ATP binding site
- Tyrosine-protein kinase, active site
SCOP: Protein kinases, catalytic subunit
