PDBe 2qo7

X-ray diffraction
1.6Å resolution

Human EphA3 kinase and juxtamembrane region, dephosphorylated, AMP-PNP bound

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ephrin type-A receptor 3 Chain: A
Molecule details ›
Chain: A
Length: 373 amino acids
Theoretical weight: 42.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P29320 (Residues: 577-947; Coverage: 39%)
Gene names: EPHA3, ETK, ETK1, HEK, TYRO4
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments


1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: P21
Unit cell:
a: 53.736Å b: 38.225Å c: 76.029Å
α: 90° β: 102.04° γ: 90°
R-values:
R R work R free
0.186 0.184 0.224
Expression system: Escherichia coli BL21(DE3)