› 2qn7

X-ray diffraction
1.83Å resolution

Glycogen Phosphorylase b in complex with N-4-hydroxybenzoyl-N'-4-beta-D-glucopyranosyl urea

Released:
DOI: 10.2210/pdb2qn7/pdb
PDB entry 2qn7 coloured by chain, front view.
PDB entry 2qn7 coloured by chain, side view.
PDB entry 2qn7 coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Entry authors: Chrysina ED, Tiraidis K, Alexacou K-M, Zographos SE, Leonidas DD, Oikonomakos NG

Function and Biology Details

Reaction catalysed: 
((1->4)-alpha-D-glucosyl)(n) + phosphate = ((1->4)-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132556 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycogen phosphorylase, muscle form Chain: A
Molecule details ›
Chain: A
Length: 842 amino acids
Theoretical weight: 97.29 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P00489 (Residues: 2-843; Coverage: 100%)
Gene name: PYGM
Sequence domains: Carbohydrate phosphorylase
Structure domains: Glycogen Phosphorylase B;

Ligands and Environments


Cofactor: Ligand PLP 1 x PLP
2 bound ligands:
Ligand HBZ 1 x HBZ
Ligand IMP 1 x IMP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P43212
Unit cell:
a: 128.335Å b: 128.335Å c: 116.615Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.204 0.23

Quick links